Founded Year

2019

Stage

Series B | Alive

Total Raised

$321M

Valuation

$0000 

Last Raised

$221M | 3 yrs ago

Revenue

$0000 

Mosaic Score
The Mosaic Score is an algorithm that measures the overall financial health and market potential of private companies.

-11 points in the past 30 days

About Orna Therapeutics

Orna Therapeutics is a biotechnology company involved in the development of circular RNA therapeutics and lipid nanoparticle (LNP) delivery systems. The company's offerings include engineered circular RNA (oRNA) medicines meant to treat various diseases and LNP technologies that deliver these RNA therapies to targeted sites in the body. Orna Therapeutics serves sectors related to oncology, autoimmune disease treatment, and genetic disorders. It was founded in 2019 and is based in Cambridge, Massachusetts.

Headquarters Location

620 Memorial Drive 2nd Floor

Cambridge, Massachusetts, 02139,

United States

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Expert Collections containing Orna Therapeutics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Orna Therapeutics is included in 1 Expert Collection, including Unicorns- Billion Dollar Startups.

U

Unicorns- Billion Dollar Startups

1,309 items

Orna Therapeutics Patents

Orna Therapeutics has filed 17 patents.

The 3 most popular patent topics include:

  • molecular biology
  • rna
  • biotechnology
patents chart

Application Date

Grant Date

Title

Related Topics

Status

11/3/2023

12/31/2024

Molecular biology, RNA, Biotechnology, Gene expression, Genetics

Grant

Application Date

11/3/2023

Grant Date

12/31/2024

Title

Related Topics

Molecular biology, RNA, Biotechnology, Gene expression, Genetics

Status

Grant

Latest Orna Therapeutics News

Orna Therapeutics Announces Encore Presentation at the American College of Rheumatology Annual Meeting Supporting its in vivo CAR Therapy Approach in Autoimmune Diseases

Oct 24, 2025

News provided by Share this article Share toX WATERTOWN, Mass., Oct. 24, 2025 /PRNewswire/ -- Orna Therapeutics, a leading biotechnology company developing a proprietary pipeline of in vivo therapies across a broad range of autoimmune and oncology indications, today announced an upcoming presentation at the American College of Rheumatology (ACR) Annual Meeting being held October 24-29, 2025, in Chicago, Illinois. This dataset is a broader update on Orna's lead program, ORN-252, as it continues toward clinical entry in the first half of 2026. Presentation Details (encore): Speaker: Isin Dalkilic-Liddle, Ph.D., Vice President, Head of Discovery Sciences, Orna Therapeutics Date/Time: Monday, October 27, 2025, 10:30 AM – 12:30 PM CDT Session Name: (0934-0954) Systemic Lupus Erythematosus – Animal Models Poster Location: Hall F1 About Orna Therapeutics Orna Therapeutics is dedicated to designing and delivering a new class of fully engineered circular RNA (oRNA®) therapeutics to unlock the potential of RNA medicine to treat diseases anywhere in the body. Orna's oRNA transcripts have advantages over traditional mRNA approaches, including simplified production, improved formulation into lipid nanoparticles, and superior protein expression. Its industry-leading LNP-based delivery systems and comprehensive editing programs position Orna to advance novel RNA medicines with vast potential to transform patient care. To learn more, visit  www.ornatx.com  and follow Orna Therapeutics on  X  and  LinkedIn . Orna Therapeutics Investor Contact:

Orna Therapeutics Frequently Asked Questions (FAQ)

  • When was Orna Therapeutics founded?

    Orna Therapeutics was founded in 2019.

  • Where is Orna Therapeutics's headquarters?

    Orna Therapeutics's headquarters is located at 620 Memorial Drive, Cambridge.

  • What is Orna Therapeutics's latest funding round?

    Orna Therapeutics's latest funding round is Series B.

  • How much did Orna Therapeutics raise?

    Orna Therapeutics raised a total of $321M.

  • Who are the investors of Orna Therapeutics?

    Investors of Orna Therapeutics include Merck, MPM BioImpact, Kite Pharma, Pagsgroup, Astellas Venture Management and 6 more.

  • Who are Orna Therapeutics's competitors?

    Competitors of Orna Therapeutics include Avidity Biosciences, CircNova, Strand Therapeutics, Harness Therapeutics, Laronde and 7 more.

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